Woman receives 3D-printed ear transplant made from human cells

News Photo: Woman receives 3D-printed ear transplant made from human cells

THURSDAY, June 2, 2022 (HealthDay News)

A 3D-printed ear made with the patient’s own cells was transplanted into a 20-year-old woman, according to the company that made the ear.

The feat announced on June 2 by 3DBio Therapeutic of New York is believed to be the first known example of a 3D-printed implant made from living tissue. Experts hailed it as a major breakthrough in the field of tissue engineering.

“It’s definitely a big deal,” said Adam Feinberg, professor of biomedical engineering and materials science and engineering at Carnegie Mellon University in Pittsburgh. The New York Times.

“It shows that this technology is no longer an ‘if,’ but a ‘when,'” said Feinberg, co-founder of Massachusetts-based FluidForm. regenerative medicine company that also uses 3D printing. It is not affiliated with 3DBio.

The transplant patient is from Mexico and was born with a small, misshapen right ear. She received her new ear in March as part of the first clinical trial of a medical application of this technology, the Time reported.

The new ear was designed to precisely match the woman’s left ear. It will continue to regenerate cartilage tissue and will look and feel like a natural ear, according to 3DBio.

Because the transplant used cells from the patient’s ear, the body is unlikely to reject it, doctors and company officials noted.

3DBio did not reveal the technical details of the process. He said the data would be published in a medical journal after the completion of an ongoing clinical trial in 11 patients, the Time reported.

US regulators reviewed the trial’s design and set strict manufacturing standards, according to 3DBio.

“It’s so exciting, sometimes I have to calm down a bit,” said trial leader Dr Arturo Bonilla. Time. The pediatric reconstructive ear surgeon in San Antonio performed the woman’s implant surgery.

“If all goes as planned, it will revolutionize the way it’s done,” added Bonilla, who has no financial stake in 3DBio.

Company executives said further research could lead to the use of 3D printing technology to make other replacement body parts, including spinal discs, nose and knee cartilage, as well as reconstructive tissue for lumpectomies, and possibly even vital organs such as the liver, kidneys. and pancreas.

Other 3D printed tissue implants are in development, but this appears to be the first tested in a clinical trial, James Iatridis told the Time. He heads a spine bioengineering lab at the Icahn School of Medicine at Mount Sinai in New York.

Preliminary trial evaluates reconstruction procedure for patients with microtia, a rare birth defect in which one or both outer ears are missing or underdeveloped. About 1,500 babies are born with microtia in the United States each year.

More information

The University of Pittsburgh has more on regenerative medicine.

SOURCES: The New York Times; 3DBio Therapeutics, press release, June 2, 2022

By Robert Preidt Health Day Journalist

Medical news
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